Hiroshi Kurihara Selected Research

1,3,7,9-tetramethyluric acid (tetramethyluric acid)

10/2020	Theacrine, a purine alkaloid from kucha, protects against Parkinson's disease through SIRT3 activation.
1/2018	Theacrine protects against nonalcoholic fatty liver disease by regulating acylcarnitine metabolism.

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Hiroshi Kurihara Research Topics

Disease

12	Neoplasms (Cancer) 01/2022 - 04/2002
8	Inflammation (Inflammations) 01/2021 - 04/2010
7	Infections 12/2020 - 01/2015
6	Human Influenza (Influenza) 01/2020 - 04/2011
5	Hyperglycemia 01/2022 - 05/2015
4	Virus Diseases (Viral Diseases) 01/2019 - 04/2011
4	Body Weight (Weight, Body) 08/2015 - 09/2002
3	Neural Tube Defects (Exencephaly) 01/2022 - 02/2004
3	Parkinson Disease (Parkinson's Disease) 04/2021 - 06/2020
3	Mitochondrial Diseases (Mitochondrial Disease) 04/2021 - 12/2010
3	Edema (Dropsy) 08/2014 - 09/2009
2	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2021 - 10/2020
2	Breast Neoplasms (Breast Cancer) 07/2019 - 01/2016
2	Non-alcoholic Fatty Liver Disease 01/2018 - 08/2015
2	Cardiomegaly (Heart Hypertrophy) 09/2014 - 01/2013
2	Hypertrophy 09/2014 - 01/2013
2	Glucose Metabolism Disorders 10/2013 - 01/2011
2	Uveitis 10/2011 - 04/2010
2	Neoplasm Metastasis (Metastasis) 03/2011 - 04/2002
1	Liver Cirrhosis (Hepatic Cirrhosis) 07/2022
1	Diabetes Complications 01/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2022
1	Gouty Arthritis 01/2021
1	Arthritis (Polyarthritis) 01/2021
1	Alcoholic Liver Diseases (Alcoholic Liver Disease) 08/2020
1	Liver Failure 08/2020
1	Drug Overdose 01/2020
1	Chemical and Drug Induced Liver Injury 01/2020
1	Ovarian Neoplasms (Ovarian Cancer) 07/2019
1	Multiple Myeloma 07/2019
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/2019
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2019
1	Drug-Related Side Effects and Adverse Reactions 10/2018
1	Skin Diseases (Skin Disease) 01/2018

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 07/2019 - 01/2012
5	LipopolysaccharidesIBA 08/2014 - 09/2009
4	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2022 - 01/2018
4	Pharmaceutical PreparationsIBA 12/2020 - 10/2011
4	TeaIBA 10/2020 - 09/2002
4	Caffeine (No Doz)FDA LinkGeneric 01/2018 - 09/2002
4	CarnosineIBA 01/2018 - 01/2011
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 05/2015
3	AlkaloidsIBA 10/2020 - 01/2018
3	InterferonsIBA 01/2020 - 12/2017
3	Antiviral Agents (Antivirals)IBA 01/2020 - 04/2017
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2019 - 10/2011
3	Croton OilIBA 08/2014 - 09/2009
3	CarrageenanIBA 01/2012 - 02/2009
2	Sorbitol (Yal)FDA Link 01/2022 - 01/2016
2	Acyclovir (Aciclovir)FDA LinkGeneric 12/2020 - 10/2018
2	purineIBA 10/2020 - 01/2018
2	Sirtuin 3IBA 10/2020 - 01/2018
2	1,3,7,9-tetramethyluric acid (tetramethyluric acid)IBA 10/2020 - 01/2018
2	LipidsIBA 08/2020 - 08/2015
2	goitrinIBA 01/2019 - 04/2017
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2018 - 01/2014
2	AntioxidantsIBA 01/2016 - 10/2011
2	2,2'-azobis(2-amidinopropane) (ABAP)IBA 09/2014 - 01/2013
2	arenobufaginIBA 06/2013 - 05/2011
2	LignansIBA 10/2011 - 03/2011
2	DinitrofluorobenzeneIBA 09/2009 - 05/2008
2	Anti-Allergic Agents (Antiallergic Agents)IBA 09/2009 - 05/2008
1	NAD (NADH)IBA 01/2022
1	Aldehyde Reductase (Aldose Reductase)IBA 01/2022
1	Malondialdehyde (Propanedial)IBA 01/2022
1	GlucocorticoidsIBA 01/2022
1	Hormones (Hormone)IBA 01/2022
1	G(M1) GangliosideIBA 04/2021
1	Therapeutic UsesIBA 04/2021
1	SynucleinsIBA 04/2021
1	Uric Acid (Urate)IBA 01/2021
1	celastrolIBA 01/2021
1	InflammasomesIBA 01/2021
1	TriterpenesIBA 01/2021
1	NucleosidesIBA 12/2020
1	baicaleinIBA 12/2020
1	penciclovir (Denavir)FDA Link 12/2020
1	Adenosine Triphosphatases (ATPase)IBA 12/2020
1	Cardiac GlycosidesIBA 12/2020
1	IronIBA 08/2020
1	levodopa drug combination benserazideIBA 06/2020
1	tianma goutengIBA 06/2020
1	CorticosteroneIBA 01/2020
1	bafilomycin A1IBA 01/2020
1	clausenamideIBA 01/2020
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020
1	UbiquitinIBA 01/2020
1	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020
1	ProdrugsIBA 07/2019
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 07/2019
1	Nitric Oxide DonorsIBA 07/2019
1	CaspasesIBA 07/2019
1	Autophagy-Related ProteinsIBA 07/2019
1	Caspase 3 (Caspase-3)IBA 07/2019
1	ErbB Receptors (EGF Receptor)IBA 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019

Therapy/Procedure

7	Therapeutics 01/2021 - 01/2016
3	Drug Therapy (Chemotherapy) 01/2018 - 06/2013
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 06/2020 - 06/2013
2	Oral Administration 01/2015 - 04/2002